Sperm have no antigens


Another choice is an antiglobulin reaction test done on blood. The CV antigen is also expressed in murine sperm [ 42 ] suggesting a feasibility of animal model for studying its immunocontraceptive potential. Before acrosome formation, SAMP32 expression did not occur. The identification of sperm antigens relevant to fertilization opens up opportunities also for diagnosis and treatment of immune infertility. Since recombinant proteins are lacking the carbohydrate moieties, their further analysis in much simpler. Is spermatozoa foreign for the female body or not?
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Why is it that sperms are not considered foreign (antigens) by the immune system of women?

Expression of sperm protein 17 Sp17 in ovarian cancer. The immunolocalization of SPAG9 protein was restricted to sperm head and not in any other cell types of seminiferous tubules. Most investigators have found no evidence for any participation of the ABO blood group antigens in cases of sterility. For Western blotting, 0. Paraffin-embedded sections of normal testis positive control and ovarian tumor samples were analyzed for the localization of SPAG9 protein using anti-SPAG9 antibody. You can read the full text of this article if you:
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Antisperm Antibodies - Immunity to Sperm - Infertility

By immunoblotting with ASA from seminal plasma samples of infertile men, several membrane antigens were recognized. Antisperm antibodies ASA are the main cause of immunological infertility, as they impair sperm function by binding to the sperm membrane. In another series of 46 cases with primary unexplained infertility agglutinating antibodies were found in Immunogenicity studies in rats showed the generation of antibodies against recombinant SPAG9 8 ,
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Sperm have no antigens
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Sperm have no antigens
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Sperm have no antigens



Description: In the present study, we analyzed the expression and in vivo immunogenicity of SPAG9 in EOC patients with its eventual application in the presymptomatic detection of ovarian cancer. The membrane preparation was performed as previously described Hinsch et al. Identification of T-cell Antigens by Minigene Screening. The blots were exposed to seminal plasma samples from patients and controls diluted 1:

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